The AstroPath Pipeline was developed to process whole slide multiplex immunofluorescence data from microscope to database at single cell resolution.
Constructing Neoantigen Vaccine Pipeline with pVACtools
the peptide immune annotator pipeline (PIA-P) a collection of bash and Python scripts used running peptide HLA interaction from a variety of inputs
Glioblastoma (GBM) remains lethal despite multimodal therapy, with median survival under 15 months. Immunotherapy has failed in over 100 clinical trials due to three fundamental barriers: inadequate immune priming in "cold" tumors, blood–brain barrier (BBB) exclusion of therapeutics, and profound local immunosuppression.
🔬 First computational framework for p62/SQSTM1 condensate-mediated PD-L1 regulation | GPU-accelerated LLPS predictions | TCGA analysis (n=100) | Publication-ready (PLoS Comp Bio → Nature Comm) | Fast, Precise, Truthful
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