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Chromnitron

This repository contains the official implementation of Chromnitron and its associated data-processing pipeline, Chrom2vec. For early testing, only the inference pipeline for Chromnitron and ATAC-seq processing component for Chrom2Vec are included. Please stay tuned for upcoming full release.

Read our pre-print on biorxiv.

Quick Start

For those looking to get started with Chromnitron quickly, we recommend the following resources:

  • Google Colab: Explore Chromnitron's features in an interactive environment Colab.
  • Local Inference: For local setup, refer to the detailed instructions in the Chromnitron README.
  • Custom Analysis: If you want to use Chromnitron with your own ATAC-seq data, please refer to the Chrom2Vec README.

Repository Overview

This repository is organized into two sub-repositories:

  • chromnitron/: This directory holds the core Chromnitron model, designed for predicting chromatin-associated protein binding.
  • chrom2vec/: This directory contains the Chrom2vec pipeline, essential for processing raw sequencing data into a format suitable for Chromnitron.

For more detailed information on each component, please see the respective README files under each subrepo:

  • chromnitron/README.md
  • chrom2vec/README.md

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A multimodal model predicting chromatin-associated proteins binding on the human genome.

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