BioPatch is a synthetic fusion protein designed to enable self-healing textiles.
It combines domains from spider silk, resilin, and mussel foot proteins to mimic nature’s best materials — and make fabrics that heal like skin.
🌍 Textile waste is one of the biggest environmental problems of our time.
👕 Clothing rips, degrades, and is discarded.
What if it could heal instead?
BioPatch is a modular fusion protein:
- 🧱 MaSp1 (Spider Silk) – Strength
- 🌀 Resilin – Elastic recoil
- 🎯 Mfp-3 – Sticky, surface-adhesive tail
- 🔗 Linked with GGGGS peptides for motion
- ✅ Full protein folded with pLDDT 82.26
- ✅ Simulated with CABS-flex
- Stable core (MaSp1)
- Elastic midsection (Resilin)
- Flexible adhesive tail (Mfp-3)
- ✅ RMSF > 7 Å at healing regions
Conceptual sketch showing BioPatch's healing design
RMSF plot from CABS-flex simulation — confirms flexibility in healing domains
📥 View the complete pitch deck (PDF)
Explore the story, science, and future vision of BioPatch in one concise deck.
| Folder | What’s Inside |
|---|---|
/data/ |
Simulation outputs, RMSF plots, .pdb files |
/variants/ |
Fusion protein sequences + design notes |
/docs/ |
Slide deck, design sketch, visuals |
/notebooks/ (optional) |
Analysis or visualization notebooks |
This is an open-source research project. You can:
- Remix the design (BioPatch P.2, P.3…)
- Express it in a lab
- Test on real fabrics
- Help document or visualize
- Run new simulations
Fork this repo or submit a pull request. Let’s build together.
This project is licensed under the MIT License.
Use it, remix it, build with it — just give credit and include the original license.
This project was born from pure curiosity and built using free tools.
Protein design powered by open AI and open science.
Want to collaborate, contribute, or run tests?
Drop an Issue or contact me directly.