DoReMiTra

DoReMiTra: A curated data package for radiation DOse REsponse Measured In TRAnscriptomics

It is an R data package providing access to curated transcriptomic datasets related to blood radiation, with a focus on neutron, x-ray, and gamma ray studies. It is designed to facilitate radiation biology research and support data exploration and reproducibility in radiation transcriptomics.

All datasets are provided as SummarizedExperiment objects, allowing seamless integration with the Bioconductor ecosystem.

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Installation

You can install the development version of DoReMiTra from GitHub using:

# Install devtools if not already installed
install.packages("devtools")

# Install DoReMiTra from GitHub
devtools::install_github("AhmedSAHassan/DoReMiTra")

Overview

The package includes preprocessed and annotated datasets from public repositories (primarily GEO), with harmonized metadata and consistent formatting. All the datasets will contain the following information in a uniform way:

✅ Radiation type (neutron, x-ray, gamma ray)

✅ Dose

✅ Time point

✅ Organism (e.g., human, mouse)

✅ Experimental setting (InVivo, ExVivo)

✅ Sex (Male, Female)

Code of Conduct

Please note that the DoReMiTra project is released with a Contributor Code of Conduct. By contributing to this project, you agree to abide by its terms.