Skip to content

adapt: already growing with glucose but model.optimize() = 0 #171

@danfrks

Description

@danfrks

Hi,

I am still having some problems with gapseq adapt.

I generated a draft model and when I use gapseq adapt this is the output I get:

Warning in add_growth(mod.out, add.met.id = sub.id, weights = rxn.weights.file, : Model is already growing with cpd00027 D-Glucose Warning: No changes made

However, solving with biomass as the objective function in cobrapy gives 0 flux.

model.medium = {'EX_cpd00009_e0': 100.0,
'EX_cpd00027_e0': 10.0,
'EX_cpd00030_e0': 100.0,
'EX_cpd00034_e0': 100.0,
'EX_cpd00048_e0': 100.0,
'EX_cpd00149_e0': 100.0,
'EX_cpd10516_e0': 100.0,
'EX_cpd00067_e0': 100.0,
'EX_cpd00971_e0': 100.0,
'EX_cpd00013_e0': 100.0,
'EX_cpd00063_e0': 100.0,
'EX_cpd00058_e0': 100.0,
'EX_cpd10515_e0': 100.0,
'EX_cpd00205_e0': 100.0,
'EX_cpd00099_e0': 100.0,
'EX_cpd00531_e0': 100.0,
'EX_cpd00254_e0': 100.0,
'EX_cpd00001_e0': 100.0,
'EX_cpd00007_e0': 100.0}

Is this expected behaviour, since the solution is null rather than infeasible?

Many thanks in advance,

Daniel

Metadata

Metadata

Assignees

No one assigned

    Labels

    No labels
    No labels

    Projects

    No projects

    Milestone

    No milestone

    Relationships

    None yet

    Development

    No branches or pull requests

    Issue actions