diff --git a/src/tests/GC/Regressions/Github/Runtime_76219/Runtime_76219.csproj b/src/tests/GC/Regressions/Github/Runtime_76219/Runtime_76219.csproj
index aefac61c542f2b..657d4ca65cbad7 100644
--- a/src/tests/GC/Regressions/Github/Runtime_76219/Runtime_76219.csproj
+++ b/src/tests/GC/Regressions/Github/Runtime_76219/Runtime_76219.csproj
@@ -5,6 +5,9 @@
     <Optimize>True</Optimize>
     <!-- Move it out of CI for 78899 -->
     <CLRTestPriority>1</CLRTestPriority>
+    <!-- Test crashes on osx arm64 under GC stress even though the test body is skipped via ActiveIssue. -->
+    <!-- ActiveIssue https://github.com/dotnet/runtime/issues/78899 -->
+    <CLRTestTargetUnsupported>true</CLRTestTargetUnsupported>
 
     <!-- This test needs GCStress mode but it doesn't take long to execute
          so is fine to keep it in the inner loop -->