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KunduKundu
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updated formatting
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SigProfilerAssignment/decompose_subroutines.py

Lines changed: 10 additions & 19 deletions
Original file line numberDiff line numberDiff line change
@@ -229,7 +229,6 @@ def signature_plotting_text(value, text, Type):
229229
name_list = []
230230
total = np.sum(np.array(value))
231231
for i in value:
232-
233232
if Type == "integer":
234233
i = int(i)
235234
p = round(i / total * 100, 1)
@@ -243,7 +242,6 @@ def signature_plotting_text(value, text, Type):
243242

244243

245244
def make_letter_ids(idlenth=10, mtype="SBS96"):
246-
247245
listOfSignatures = []
248246
letters = list(string.ascii_uppercase)
249247
letters.extend([i + b for i in letters for b in letters])
@@ -422,7 +420,6 @@ def signature_decomposition(
422420
merger = PdfMerger()
423421

424422
for i, j in zip(range(signatures.shape[1]), denovo_signature_names):
425-
426423
# Only for context SBS96
427424
if signatures.shape[0] == 96:
428425
lognote = open(
@@ -566,16 +563,16 @@ def signature_decomposition(
566563

567564
if mtype == "1536":
568565
mtype_par = "1536"
569-
# elif mtype == "288":
570-
# mtype_par = "288"
571-
# elif mtype == "96":
572-
# mtype_par = "96"
573-
# elif mtype == "DINUC" or mtype == "78":
574-
# mtype_par = "78"
575-
# elif mtype == "INDEL" or mtype == "83":
576-
# mtype_par = "83"
577-
# elif mtype == "CNV" or mtype == "48":
578-
# mtype_par = "48"
566+
elif mtype == "288":
567+
mtype_par = "288"
568+
elif mtype == "96":
569+
mtype_par = "96"
570+
elif mtype == "DINUC" or mtype == "78":
571+
mtype_par = "78"
572+
elif mtype == "INDEL" or mtype == "83":
573+
mtype_par = "83"
574+
elif mtype == "CNV" or mtype == "48":
575+
mtype_par = "48"
579576
elif mtype == "SV" or mtype == "32":
580577
mtype_par = "32"
581578
else:
@@ -586,7 +583,6 @@ def signature_decomposition(
586583
and make_decomposition_plots == True
587584
and signature_database is None
588585
):
589-
590586
# reformat the first column of cosmic signature dataframe
591587
cosmic_sigs_DF = sigDatabases_DF.copy(deep=True)
592588
cosmic_sigs_DF.columns = ["MutationType"] + cosmic_sigs_DF.columns[
@@ -765,7 +761,6 @@ def make_final_solution(
765761
denovo_refit_option=True,
766762
exome=False,
767763
):
768-
769764
if processAvg.shape[0] == allgenomes.shape[0] and processAvg.shape[0] != 96:
770765
collapse_to_SBS96 = False
771766

@@ -862,7 +857,6 @@ def make_final_solution(
862857

863858
init_decomposed_sigs = []
864859
for de_novo_sig in init_sigs:
865-
866860
init_decomposed_sigs = union(
867861
init_decomposed_sigs, list(attribution[de_novo_sig])
868862
)
@@ -1459,7 +1453,6 @@ def make_final_solution(
14591453
custom_signatures_plot(processes, layer_directory + "/Signatures")
14601454

14611455
if export_probabilities == True:
1462-
14631456
probability = probabilities(
14641457
processAvg, exposureAvg, index, allsigids, allcolnames
14651458
)
@@ -1645,7 +1638,6 @@ def cor_sim(a, b):
16451638

16461639
################################################### Generation of probabilities for each processes given to A mutation type ############################################
16471640
def probabilities(W, H, index, allsigids, allcolnames):
1648-
16491641
# setting up the indices
16501642
rows = index
16511643
cols = allcolnames
@@ -1658,7 +1650,6 @@ def probabilities(W, H, index, allsigids, allcolnames):
16581650

16591651
result = 0
16601652
for i in range(H.shape[1]): # here H.shape is the number of sample
1661-
16621653
M = genomes[:, i][np.newaxis]
16631654
probs = W * H[:, i] / M.T
16641655
probs = pd.DataFrame(probs)

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